• Treating ailments -  North American First Nations people used wild sarsaparilla to treat a variety of ailments, including heart pain, stomach upset, toothaches, sore throats, pneumonia, and infections.
• Promoting sexual health - Wild sarsaparilla was used to promote sexual health.
• Detoxifying - Wild sarsaparilla was used to detoxify the body and purify metabolic toxins.
• Treating skin problems - Wild sarsaparilla was used as a poultice to treat sores, burns, itchy skin, ulcers, and eczema.
• Treating pulmonary diseases - Wild sarsaparilla was used to treat pulmonary diseases, asthma, and rheumatism.
• Treating cystitis - Wild sarsaparilla was used as a homeopathic remedy to treat cystitis. 

It has a root beer flavour and is sometimes used as one of the herbs in those brews.
Further research into the medicinal uses of Wild Sarsaparilla root is needed to better understand definitively the plant’s health benefits. There is not enough scientific information available to guarantee safety for pregnant and breastfeeding women.